By W. Schramm, H. Krebs (auth.), Professor Dr. med. Inge Scharrer, Professor Dr. med. Wolfgang Schramm (eds.)
This e-book includes the contribution to the thirty fifth Hemophilia Symposium, Hamburg 2004. the most issues are epidemiology, chance of infections and inhibitors in hemophilia, power hemophilic synovitis and long term result of orthopedic remedy, laboratory diagnostics and pediatric hemostaseology. the quantity is rounded off through a number of loose papers and posters on hemophilia and hemorrhagic problems and inhibitors in hemophilia.
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Extra resources for 35th Hemophilia Symposium: Hamburg 2004
Two case reports of presumptive transmission of vCJD in humans were subsequently published in 2004 [7, 8], the second case report also being particularly important as this described the first case of vCJD in a subject heterozygous for methionine/valine at codon 129 in the prion gene and implying a wider susceptibility in the general population than previously reported. Of course, the fact that vCJD can be transmitted by a transfusion of whole blood does not automatically imply that fractionated plasma-derived products carry a similar risk.
Prion protein biology. Cell 1998; 93: 337–348 20. Remington KM, Trejo SR, Buczynski G, Li H, Osherhoff WP, Brown JP, Renfrow H, Reynolds R, Pifat DY. Inactivation of West Nile virus, vaccinia virus and viral surrogates for relevant and emergent viral pathogens in plasma derived products. Vox sang 2004; 87: 10–18 21. Warrell MJ, Warrell DA. Rabies and other lyssavirus diseases. Lancet 2004; 363: 959–969 22. Wilson K, Ricketts MN. Transfusion transmission of vCJD: a crisis avoided ? Lancet 2004; 364: 477–479 nvCJD and Blood Products in the UK P.
This data was merged with existing data returning to 1982 and analyzed statistically. In the 2003/2004 survey, a total number of 8445 patients (including possible double registrations) have been reported from the participating centers. Results Participating centers Since the first survey the number of participating centers has increased every year with a particularly rise in 1991 when the hemophilia treatment centers of the former East Germany joined in. Today these centers contribute a significant portion of the overall data (Fig.